Pathology and Biospecimen Core


The Path Core is a centralized service that is responsible for the standardized acquisition, storage, characterization and distribution of human tissues to HNC investigators. The success of any clinical trial hinges on investigators producing accurate and reliable preclinical data. The Path Core’s mission for biospecimen quality and efficiency is critical in helping investigators achieve these results.


Specific Aims:

  • Aim 1: To collect, process, preserve and distribute HNC biospecimens.

  • Aim 2: To provide and maintain a centralized HN SPORE biospecimen bioinformatics database.

  • Aim 3: To provide a full range of expert services for biospecimen characterization.

  • Aim 4: To serve and support HN SPORE investigators and collaborate with other investigators in the HNC research community.

Team Pictures:

The HN SPORE Path Core would not be able to collect the number of biospecimens needed for Head and Neck Cancer research without the help of UW Health ENT nursing staff. They help by asking patients if they are interested in donating leftover cancer tissue that is not needed for clinical application. Investigators use this tissue in head and neck cancer research to improve treatments for future patients. The ENT nursing staff works with the Cancer Center WiscShare

ENT nurses work with SPORE Path Core to ask HN Cancer Patients to donate leftover biospecimens for research
Right to left: Everlyne Nkadori, TSB Biobank Manager; Linda Essert-Dobson, RN; Maria Luellen, RN; Lisa Bua, RN; Heather Geye, MS; Jackie Kiltz, RN


Paul Lambert, PhDPaul Lambert, PhD

Director, McArdle Laboratory for Cancer Research
Professor and Chair of Oncology
University of Wisconsin


Darya Buehler, MDDarya Buehler, MD

Associate Professor of Pathology & Laboratory Medicine
University of Wisconsin


Tiffany Glazer, MDTiffany Glazer, MD

Head and Neck Surgeon
Assistant Professor of Surgery-Otolaryngology
University of Wisconsin


Randall Kimple, MD, PhDRandall Kimple, MD, PhD

Radiation Oncologist
Associate Professor of Human Oncology
University of Wisconsin



Karla Esbona, PhDKarla Esbona, PhD

Scientific Manager, TRIP Lab
Department of Pathology & Laboratory Medicine
University of Wisconsin

Request HN SPORE Pathology Resources

  • HNC Cell Lines
  • HNC Patient Derived Xenografts
  • HNC Tissue Microarrays
  • HNC histology services
  • HNC Biospecimens

Acknowledge Pathology Core for Publications, Posters and Presentations:

This project was supported by the Specialized Program of Research Excellence (SPORE) program, through the NIH National Institute for Dental and Craniofacial Research (NIDCR) and National Cancer Institute (NCI), grant P50CA278595. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.